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10.1212/WNL.0000000000001055 31 HanaokaK.SasakuraK.SuwanaiY.Toma-FukaiS.ShimamotoK.TakanoY.et al (2017)

These damaging compounds can lead to graying hair, as oxidative stress accelerates apoptosis (cell death) of melanocyte stem cells

While NAD does not regenerate blood vessels, it plays a vital role in supporting endothelial cell function, improving mitochondrial oxygen utilization, and enhancing nitric oxide signalingkey factors that help tissues use available circulation more effectively

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It moves those fluids out faster, leaving the effects for a shorter stretch of time